As @pt3r said it’s possible, for most of patches and for orac. The best you can do is reading the manual about this or watching @thetechnobear YouTube tutorial about orac.
Depends on what midi controller you want to use you can use usb or need a midi/usb cable / interface.
you’ll need to configure organelle for multiple midi devices, this I have detailed in this thread:
then Orac 2.0 supports midi learn, you can therefore learn all parameters you want
(iirc, it might be limited to 127 midi cc on midi ch1 at the moment, but thats quite a lot of controls)
so you can easily map things like a modules gain or bypass to a midi control.